Research Article

In Vitro Study of Combined Application of Bevacizumab and 5-Fluorouracil or Bevacizumab and Mitomycin C to Inhibit Scar Formation in Glaucoma Filtration Surgery

Table 4

Cell viability of human umbilical vein endothelial cells (HUVECs) after treatment with bevacizumab (BVZ), 5-fluorouracil (5-Fu), BVZ/5-Fu, mitomycin C (MMC), and BVZ/MMC.

Medicine and concentration (mg/ml)Absorbance at 570 nm (ratio, compared to PBS)Medicine and concentration (mg/ml)Absorbance at 570 nm (ratio, compared to PBS)

BVZ0.0251.0652 ± 0.0792
0.251.0030 ± 0.0598
2.51.1882 ± 0.0699
5-Fu0.050.9645 ± 0.0739BVZ2.5/5-Fu0.050.7194 ± 0.0929
0.50.9938 ± 0.04920.50.6249 ± 0.0701
50.8967 ± 0.017250.4385 ± 0.0108
MMC0.000021.1165 ± 0.0726BVZ2.5/MMC0.000020.5989 ± 0.0734
0.00021.0582 ± 0.11620.00020.6698 ± 0.0960
0.0020.9254 ± 0.06760.0020.6613 ± 0.1846