Retinal Sensitivity Loss Correlates with Deep Capillary Plexus Impairment in Diabetic Macular Ischemia

Figure 3

Microperimetry map of the 3 × 3 area spanned with optical coherence tomography angiography (OCTA) in diabetic patients with various stages of superficial and deep capillary plexus impairment and retinal sensitivity reduction. The first case on the top of the image represents the normal control with no retinal sensitivity and no retinal vascular and anatomical abnormalities. Left column: microperimetry maps show a progressive reduction of the retinal sensitivity from the top to the bottom. Middle column: enface deep capillary plexus images highlighting the abnormalities of no flow areas at the level of the DCP corresponding to the points of reduced retinal sensitivity. The red and green lines indicate the lower reflectivity of the inner segment-outer segment and outer segment-retinal pigment epithelium junctions corresponding to zones of reduced capillary flow signal on the structural B-scan along with alteration of the normal retinal contour. Right column: enface superficial capillary plexus images showing the overlying area in cases with or without involvement of the vascular damage.