Age-Related Physiologic Thinning Rate of the Retinal Nerve Fiber Layer in Different Levels of Myopia
Table 2
Clinical characteristics of three subgroups based on SE.
NMG (A), n = 37
MMG (B), n = 124
HMG (B), n = 62
value (A vs. B, A vs. C, B vs. C)
Age (yrs)
50 ± 13
39 ± 11
36 ± 12
<0.001
<0.001
0.133
Gender (male:female)
12 : 25
70 : 54
29 : 33
0.354
S.E (D)
0.69 ± 0.79
−2.96 ± 1.69
−8.7 ± 1.77
<0.001
<0.001
<0.001
Baseline IOP (mmHg)
15 ± 3.7
16 ± 3.0
16 ± 2.2
1.0
1.0
1.0
Follow-up mean IOP (mmHg)
14 ± 2.2
15 ± 2.5
15 ± 2.1
0.373
0.207
1
Baseline MD (dB)
−0.47 ± 1.3
−0.74 ± 1.2
−1.1 ± 1.3
0.733
0.059
0.253
Global RNFL thickness (μm)
90.2 ± 9.5
86.9 ± 10.3
82.1 ± 7.6
0.108
<0.001
0.009
RNFL thickness, superior quad. (μm)
113.1 ± 17.1
107.4 ± 17.4
100.0 ± 13.8
0.207
0.001
0.017
RNFL thickness, temporal quad. (μm)
67.4 ± 8.3
67.5 ± 12.5
71.8 ± 14.0
1.0
0.281
0.089
RNFL thickness, inferior quad. (μm)
118.2 ± 16.7
110.0 ± 17.6
99.0 ± 13.5
0.02
<0.001
<0.001
RNFL thickness, nasal quad. (μm)
62.2 ± 8.4
62.9 ± 9.7
57.5 ± 9.0
1.0
0.056
0.001
SE: spherical equivalent, D = diopters; IOP = intraocular pressure; MD = mean deviation; RNFL = retinal nerve fiber layer, quad. = quadrant. Data are presented as mean values ± standard deviation. Comparison among three groups was performed by analysis of variance with the Bonferroni method. value with the linear-by-linear association test. values with the Dunnett T3 method.
