Clinical Analysis of Castleman’s Disease of the Lacrimal Gland

Table 1

Clinical manifestations of 5 patients with CD of the lacrimal gland.

Case	1	2	3	4	5
Gender	M	F	F	F	F
Age	76	61	76	46	44
Site	OS	OU	OD	OD	OU
Time(month)	36	60	2	48	12
Neoplasm	+	+	+	+	+
Boundary	+	+	−	+	+
Pain	−	−	−	−	−
Swelling/ptosis	+	+	+	+	+
Restriction of eye movement	+	+	−	+	−
Diplopia	−	+	−	−	−
Others	Sublingual gland lobular enlargement			CMV(+)
				HSV-1(+)
				VZV(+)
Therapeutic regimen	Surgical resection	Surgical resection	Surgical resection	Surgical resection	Surgical resection
Pathological type	CD (plasma cell)	CD (hyaline-vascular)	CD (plasma cell)	CD (transformation to plasma cell tumor)	CD (plasma cell)
Prognosis	No recurrence	No recurrence	No recurrence	Recurrence	Recurrence
	Died due to cardiovascular accident			Chemotherapy	Progression to the IgG4-related eye disease
				Died due to a progressive disease
Response to glucocorticoid	+	+++	−	No use	+