Clinical Study

Evaluation of Functional Outcomes and OCT-Biomarkers after Intravitreal Dexamethasone Implant for Postoperative Cystoid Macular Edema in Vitrectomized Eyes

Table 1

Demographic data, lens status, prior treatments, mean number of injections, mean duration between surgery and onset of PCME, and between the diagnosis of PCME and first DEX injection in all eyes, and with regard to the indication for surgery.

ParameterAll eyesERMRRD

Mean age ± SD, years (range)64.8 ± 10.2 (35–90)66.2 ± 10.5 (35–90)60.5 ± 8.0 (42–75)

Sex, n (%)
 Male27 (44.3)19 (31.1)8 (13.1)
 Female34 (55.7)27 (44.3)7 (11.5)

Laterality, n (%)
 Right30 (49)23 (37.7)7 (11.5)
 Left31 (51)23 (37.7)8 (13.1)

Lens status at surgery, n (%)
 Phakic27 (44.3)24 (39.3)3 (4.9)
 Pseudophakic34 (55.7)22 (36.1)12 (19.7)

Previous treatment, n (%)43 (70.5)31 (50.8)12 (19.7)
 Topical11 (18)9 (14.7)2 (3.3)
 Parabulbous triamcinolone33 (54.1)23 (37.7)10 (16.4)
 Naive18 (29.5)15 (24.6)3 (4.9)

Mean number of injections, n ± SD1.57 ± 0.71.67 ± 0.81.3 ± 0.6
1 injection, n (%)35 (57.4)23 (37.7)12 (19.7)
2 injections, n (%)17 (27.9)15 (24.6)2 (3.3)
3 injections, n (%)9 (14.7)8 (13.1)1 (1.6)

Mean duration between surgery and onset of PCME (months)3.4 ± 3.1 (0–12)3.2 ± 3.2 (0–12)4.1 ± 2.8 (1–12)

Mean duration between the diagnosis of PCME and first DEX (months)7.7 ± 12.9 (0–44)6.5 ± 11.1 (0–44)11.5 ± 17.5 (0–18)

ERM: epiretinal membrane; RRD: rhegmatogenous retinal detachment; SD: standard deviation; PCME: postoperative cystoid macular edema; DEX: dexamethasone implant.