The Difference in Repeatability of Automated Superficial Retinal Vessel Density according to the Measurement Area Using OCT Angiography
Table 3
Repeatability of vascular density, perfusion density, and foveal avascular zone metrics according to measurement areas.
ICC
CV
CR
3 × 3 mm
6 × 6 mm
3 × 3 mm
6 × 6 mm
3 × 3 mm
6 × 6 mm
Vessel density
Total area
0.812 (0.732–0.867)
0.816 (0.739–0.871)
3.92 (3.25–4.59)
3.70 (2.88–4.53)
2.11 (1.99–2.23)
1.69 (1.57–1.81)
Fovea
0.826 (0.744–0.878)
0.741 (0.693–0.812)
8.00 (6.73–9.28)
12.75 (10.75–14.75)
2.37 (2.21–2.52)
2.70 (2.57–2.82)
Inner average
0.812 (0.733–0.868)
0.734 (0.622–0.812)
3.68 (3.06–4.31)
5.66 (4.23–7.08)
2.11 (1.99–2.34)
2.47 (2.30–2.64)
Perfusion density
Total area
0.823 (0.748–0.875)
0.832 (0.761–0.881)
3.57 (2.98–4.16)
3.81 (2.93–4.70)
0.03 (0.03–0.04)
0.04 (0.04–0.05)
Fovea
0.839 (0.761–0.886)
0.762 (0.685–0.783)
9.32 (7.90–10.74)
14.90 (12.41–17.40)
0.05 (0.04–0.05)
0.08 (0.07–0.08)
Inner average
0.803 (0.720–0.861)
0.760 (0.659–0.831)
3.41 (2.82–4.01)
5.96 (4.46–7.47)
0.04 (0.03–0.04)
0.06 (0.06–0.07)
Foveal avascular zone
Area
0.892 (0.847–0.924)
0.695 (0.630–0.817)
4.65 (3.56–5.73)
12.75 (10.09–15.41)
0.06 (0.05–0.07)
0.13 (0.12–0.14)
Perimeter
0.773 (0.607–0.875)
0.694 (0.566–0.785)
6.45 (3.98–8.92)
11.87 (8.81–14.93)
0.55 (0.48–0.61)
0.69 (0.63–0.76)
Circularity
0.757 (0.578–0.846)
0.503 (0.294–0.650)
8.53 (6.90–10.16)
10.99 (8.34–13.63)
0.17 (0.16–0.19)
0.20 (0.18–0.21)
ICC: intraclass correlation; CV: coefficient of variation; CR: coefficient of repeatability. Repeatability indicators are presented with 95% confidence intervals.
