Multimodal Imaging Features of Schnyder Corneal Dystrophy

Figure 3

In vivo confocal microscopy images (400 × 400 μm) at different scanning depths showing epithelial and stromal hyperreflective deposits and keratocyte damage in eyes with Schnyder dystrophy. (a) Epithelial wing cell layer with small round hyperreflective deposits (long thick arrows). (b) Basal epithelial cell layer with rod-shaped hyperreflective deposits (short arrows). (c) Both Bowman layer and the epithelial basement membrane (stars) appear to be undulated. (d) Thin subbasal nerves (stars). (e–h) stromal images show needle-shaped hyperreflective deposits (arrowheads), increased background reflectivity, stromal striae (thin arrows), absence of visible keratocyte nuclei, and rectangular deposits (thick arrow, only observed in patient #6). (i) Normal endothelium.