Review Article

Impact of Ophthalmic Viscosurgical Devices in Cataract Surgery

Table 3

Complication rates reported for OVDs.

Author (year)OVDsN (eyes)Adverse events (rates in %)

Auffarth (2017)Twinvisc109Ocular hypertension (12.6%), corneal edema (0.9%), cystoid macular edema (0.9%); IOP ≥ 30 mmHg in 6 hours postop (6.5%), 24 hours (0.9%), 7 days (0.9%), 30 days (0%), 90 days (0%)

DuoVisc111Ocular hypertension (17.6%), corneal edema (0.9%), inflammation (0.9%), capsule break (0.9%), bubbles in Viscoat OVD (0.9%); IOP ≥ 30 mmHg in 6 hours postop (7.2%), 24 hours (0%), 7 days (0%), 30 days (0%), 90 days (0%)

Espindola (2012)DisCoVisc39No intraoperative and postoperative complications
2% HPMC39

Hutz (1996)Methocel50Pressure peaks up to 44 mm·Hg requiring acetazolamide (Diamox) treatment occurred twice in the Healon GV group and once in the Healon group postoperatively. Peaks up to 38 mm·Hg occurred three times in the Viscoat group, and peaks up to 35 mm Hg occurred six times in the Methocel group
Viscoat50
Healon50
Healon GV50

Oshika (2004)Healon578IOP elevation (5.1%), corneal edema (2.5%), nausea and vomiting (1.3%)
Healon79IOP elevation (1.3%), corneal edema (1.3%)

Oshika (2010)DisCoVisc154IOP ≥ 30 mmHg in 5 h postop (7.2%)
Healon5163IOP ≥ 30 mmHg in 5 h postop (7.4%), mild corneal edema (0.6%), macular edema (0.6%)

Ray-Chaudhary (2006)Ophthalin51No significant difference in the number of complications between the two groups
HPMC-Ophtal52

Rainer (2007)NaHa 1%40IOP ≥ 30 mmHg in 30 mins postop (3%), 1 hour postop (5%), 2 hours postop (3%), 3 hours postop (5%), 4 hours postop (8%), 6 hours postop (13%), 8 hours postop (8%), 20–24 hours postop (0%)
2% HPMC40IOP ≥ 30 mmHg in 30 mins postop (8%), 1 hour postop (13%), 2 hours postop (23%), 3 hours postop (13%), 4 hours postop (8%), 6 hours postop (10%), 8 hours postop (10%), 20–24 hours postop (0%)

Thirumalai (2007)Healon GV415In 2 hours follow-up: IOP ≥ 30 mmHg (7.2%), IOP ≥35 mmHg (4%). In 24-hour follow-up: IOP ≥ 30 mmHg (8.8%), IOP ≥ 35 mmHg (4%). In 2-day follow-up: IOP ≥30 mmHg (7%), IOP ≥ 35 mmHg (3.5%)