Vitamin D and Glaucoma: A Critical Review of the Literature

Table 2

Summary of the reviewed clinical studies and their findings.

		Inverse association with; 1. IOP; 2. Glaucoma presence; 3. Glaucoma severity	No. of patients	Type of study	Studied population	Tested serum vit D
1	[8]	1. N	129 healthy	Nested case-control and RCT	Norway	25(OH)
		2. NA	87 low serum vit D
		3. NA	42 high serum vit D
2	[10]	1. Y	POAG 290	Cross-sectional	South Korea	25(OH)
		2. Y	Suspect 410
		3. NA	Healthy 5394
3	[6]	1. N	POAG 150	Case-control	France	25(OH)
		2. Y	Severe 99
		3. N	Moderate 51
4	[7]	1. N	Controls 164
		2. Y (in males only)	Glaucoma 1627	Cross-sectional	South Korea	25(OH)
		3. NA	Healthy 121,704
5	[9]	1. NA	POAG 79	Case-control	China	1α,25(OH)2D3
		2. Y	Healthy 71
		3. NA
		VDR polymorphisms
		BsmI ‘B’ and TaqI ’t’
6	[5]	1. Y	POAG 357	Case-control	African descent	25(OH)
		2. N	Healthy 178
		3. Y

Unspecified gonioscopic status.