Comparative Analysis of the Clinical Features and Long-Term Outcomes of Pachychoroid Neovasculopathy and Type 1 Neovascular Age-Related Macular Degeneration

Table 1

Initial observations of distinct characteristics between individuals of the pachychoroid group and the AMD group.

Category	PCN group	AMD group	value
Number of eyes (eyes)	30	60
Subfoveal choroidal thickness^† (μm)	335 ± 43	250 ± 41	<0.001
Age^§ (years)	66.7 ± 11	75.3 ± 6.9	0.001
Sex^‡ (male: female)	16 : 14	36 : 24	0.579
History of CSC^‡ (eyes, (%))	24 (80%)	9 (15%)	<0.001
BCVA^† (logMAR), F	0.39 ± 0.13	0.51 ± 0.14	0.137
Choroidal hyperpermeability^‡ (eyes, (%))	22 (73.3%)	10 (16.4%)	<0.001
Polypoidal lesion^‡ (eyes, (%))	12 (40%)	14 (23.3%)	<0.001
Presence of drusen^‡ (eyes, (%))	4 (13.3%)	35 (58.3%)	0.020

Values are presented as mean ± SD, otherwise indicated. , statistically significant value; †, analyzed by paired t-test; ‡, analyzed by Fisher’s exact test; §, analyzed by Mann–Whitney test.