Research Article

Efficacy for the Annual Relapse Rate after the Immunosuppressive Therapy in Patients Associated with Anti-AQP4 or Anti-MOG Antibody-Positive Optic Neuritis

Table 3

The efficacy of immunosuppressive therapy.

At the initiation of immunosuppressive therapyAt final visit

Median ARR of ON (first-third quartile)0.33 (0–0.45)0 (0–0)
Median ARR of ON, myelitis, and encephalitis episode (first-third quartile)0.37 (0.17–0.55)0 (0–0.13)
Mean PSL dosage (mg/day) (SD)17.8 (7.1)6.2 (2.4)
Mean logMAR BCVA (SD)
Dominant eye−0.1 (0.2)−0.1 (0.2)
Nondominant eye0.9 (1.0)0.9 (1.0)
Mean GCL + thickness (μm) (SD)
Dominant eye59.5 (12.5)57.5 (10.5)
Nondominant eye49.8 (15.3)45.4 (14.5)
Mean cpRNFL thickness (μm) (SD)
Dominant eye71.2 (21.0)74.4 (18.1)
Nondominant eye59.9 (22.1)58.0 (13.4)

ARR: annualized relapse rate, ON: optic neuritis, PSL: prednisolone, SD: standard deviation, BCVA: best-corrected visual acuity, GCL: ganglion cell layer, cpRNFL: circumpapillary retinal nerve fiber layer.