A Randomized Controlled Trial of the Effect of 0.01% Atropine Eye Drops Combined with Auricular Acupoint Stimulation on Myopia Progression
Table 2
Change in ocular parameters at different timepoints.
0.01% A (n = 50)
0.01% A + AAS (n = 50)
Spherical equivalent (D)d
Change at 1 m
−0.09 ± 0.03
−0.04 ± 0.03
0.23
<0.001
0.36
Change at 3 m
−0.20 ± 0.03
−0.13 ± 0.03
0.12
Change at 6 m
−0.38 ± 0.04
−0.25 ± 0.04
0.02
Axial length (mm)d
Change at 1 m
0.04 ± 0.04
0.03 ± 0.04
0.37
<0.001
0.46
Change at 3 m
0.12 ± 0.05
0.10 ± 0.05
0.28
Change at 6 m
0.23 ± 0.05
0.20 ± 0.05
0.15
Subfoveal choroidal thickness (μm)
Change at 1 m
−0.74 ± 2.55
2.09 ± 2.71
0.36
0.033
0.59
Change at 3 m
−3.15 ± 3.00
−1.57 ± 2.82
0.61
Change at 6 m
−9.18 ± 2.76
−7.92 ± 2.92
0.55
Average choroidal thickness (μm)
Change at 1 m
−1.27 ± 1.60
0.04 ± 1.68
0.79
Change at 3 m
−2.99 ± 1.87
−0.67 ± 1.69
0.21
0.039
0.61
Change at 6 m
−4.75 ± 2.04
−3.00 ± 1.70
0.45
Anterior chamber depth (mm)
Change at 1 m
0.01 ± 0.01
0.01 ± 0.00
0.76
Change at 3 m
0.01 ± 0.01
0.02 ± 0.00
0.82
<0.001
0.48
Change at 6 m
0.03 ± 0.01
0.03 ± 0.01
0.28
Intraocular pressure (mmHg)
Change at 1 m
−0.27 ± 0.32
0.19 ± 0.29
0.33
Change at 3 m
−0.11 ± 0.34
0.01 ± 0.33
0.80
0.17
0.18
Change at 6 m
0.93 ± 0.39
0.51 ± 0.37
0.48
Values are expressed as means ± standard error. a value tests for group difference; b value tests for time; c value tests for the interaction between treatment and time; dadjusted for age, sex, baseline spherical equivalent, number of myopic parents, and outdoor time. Significant at 0.05.
