Research Article
Efficacy of Topical Hydrocortisone in Combination with Topical Ciclosporin A for the Treatment of Dry Eye Disease in Patients with Sjögren Syndrome
Table 2
Study parameters at baseline compared between the two treatment regimens.
| | Ciclosporin A + hydrocortisone | Ciclosporin A | |
| Baseline | Eyes | 12 | 12 | | Visual Analogue Scale | 39.0 ± 20.6 | 35.9 ± 20.4 | 0.720 | Tear BUT (sec) | 2.8 ± 1.3 | 3.4 ± 1.6 | 0.410 | Fluorescein Oxford staining grade | 3.3 ± 0.5 | 3.1 ± 0.3 | 0.514 | Lissamine Oxford staining grade | 3.0 ± 0.9 | 3.0 ± 0.9 | 1.0 | Schirmer test (mm/5 min) | 3.6 ± 1.8 | 3.3 ± 1.4 | 0.590 | MG dropout rate (%) | 31.9 ± 12.7 | 33.2 ± 12.1 | 0.808 | Corneal MTF | 0.38 ± 0.11 | 0.39 ± 0.21 | 0.717 | Corneal Strehl ratio | 0.18 ± 0.13 | 0.23 ± 0.21 | 0.482 | Intraocular pressure | 14.0 ± 2.0 | 14.2 ± 2.7 | 0.932 |
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Data are presented as mean ± SD; P: difference between the treatment regimens using t test for independent samples and Mann–Whitney U test.
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