Research Article

Efficacy of Topical Hydrocortisone in Combination with Topical Ciclosporin A for the Treatment of Dry Eye Disease in Patients with Sjögren Syndrome

Table 2

Study parameters at baseline compared between the two treatment regimens.

Ciclosporin A + hydrocortisoneCiclosporin A

Baseline
Eyes1212
Visual Analogue Scale39.0 ± 20.635.9 ± 20.40.720
Tear BUT (sec)2.8 ± 1.33.4 ± 1.60.410
Fluorescein Oxford staining grade3.3 ± 0.53.1 ± 0.30.514
Lissamine Oxford staining grade3.0 ± 0.93.0 ± 0.91.0
Schirmer test (mm/5 min)3.6 ± 1.83.3 ± 1.40.590
MG dropout rate (%)31.9 ± 12.733.2 ± 12.10.808
Corneal MTF0.38 ± 0.110.39 ± 0.210.717
Corneal Strehl ratio0.18 ± 0.130.23 ± 0.210.482
Intraocular pressure14.0 ± 2.014.2 ± 2.70.932

Data are presented as mean ± SD; P: difference between the treatment regimens using t test for independent samples and Mann–Whitney U test.