Research Article

Efficacy of Topical Hydrocortisone in Combination with Topical Ciclosporin A for the Treatment of Dry Eye Disease in Patients with Sjögren Syndrome

Table 4

values of differences in study parameters between the two treatment regimens after 2 weeks and 6 months of treatment.

P (2 weeks)P (6 months)

Visual Analogue Scale0.8310.810
Tear BUT (sec)0.4430.378
Fluorescein Oxford staining grade0.7990.755
Lissamine Oxford staining grade0.7550.887
Schirmer test (mm/5 min)0.4100.843
MG dropout rate (%)0.830
Corneal MTF0.205
Corneal Strehl ratio0.486
Intraocular pressure0.9770.887

P: difference between the treatment regimens (ciclosporin A + hydrocortisone and ciclosporin A alone) using t test for independent samples and Mann–Whitney U test.