Author, year Study type Total number of patients Female gender FAF imaging modality Quadrants of RRD affected Macular status Surgery type Use of heavy fluid Use of tamponade agent Postoperative posture Shiragami [3 ] Prospective interventional case series 43 17 FC 1–2 eyes On = 12 PPV 30 Gas = 43 Sitting several minutes immediately post-op with face-down or appropriate positioning for 7 to 10 days post-op 2–31 eyes Off = 15 3–8 eyes 4–2 eyes Pandya [6 ] Retrospective case series 5 0 FC N/A Off = 5 PPV = 4 N/A Gas = 5 Face-down post-op SB = 1 Brosh [7 ] Retrospective consecutive case series 238 94 FC >2 = 91 eyes On = 71 PPV = 124 8 Gas = 117 All but 4 patients in the PPV group had immediate face-down positioning ≤2 = 138 eyes Off = 167 PR = 114 SO = 4 Schawkat [8 ] Prospective randomized controlled trial 50 14 FC 1–2 eyes Off = 50 PPV 25 Gas = 50 Log-roll postoperatively with face-down position vs. lying flat on back for 6 hours 2–23 eyes 3–17 eyes 4–8 eyes Dell’Omo [10 ] Prospective observational case series 125 26 FC 2–67 eyes On = 23 PPV 80 Gas = 97 Strict prone posture for at least 2 hours in the operating room and during the following 24 hours 3–26 eyes Off = 122† SO = 28 4–32 eye Codenotti [11 ] Prospective observational case series 23 8 cSLO 1–6 eyes On = 13 PPV 23 Gas = 14 All patients treated with gas tamponade were immediately positioned face-down 2–10 eyes Off = 10 SO = 9 3–3 eyes 4–23 eyes Sitting position was avoided for the first 24 hours Cobos [15 ] Prospective observational case series 20 N/A cSLO 1–5 eyes On = 12 PPV N/A Gas = 20 Face-down immediately post-op 2–9 eyes Off = 8 3–4 eyes 4–2 eyes Casswell [13 ] Prospective randomized controlled trial 239 68 FC + cSLO N/A Off = 239 PPV 3 Gas = 239 Face-down or support-the-break for 24 h in each group followed by support-the-break positioning for 6 days Dell’Omo [16 ] Prospective observational case series 20 8 cSLO 2.95 (0.75)‡ Off = 20 PPV 0 Gas = 20 Strict prone posture for 2 hours post-op Guber [9 ] Prospective randomized controlled study 50 14 FC 1–2 eyes Off = 50 PPV 25 Gas = 50 Group 1: Log-roll (n = 26) 2–23 eyes Group 2: Lying flat on back for at least 6 hrs (n = 24) 3–17 eyes 4–8 eyes Lee [5 ] Prospective observational case series 60 N/A FC PPV-gas in fovea-involving patients: On = 35 PPV = 51 PFCL = 16/32 PPV + GAS fovea-involving RRD Gas = 49 Face-down for >1 hr in almost all patients 1–17 eyes Off = 37§ SB = 9 SO = 2 2–9 eyes 3/4–5 eyes Shiragami [12 ] Prospective randomized controlled trial 86 33 FC 1–7 eyes On = 36 PPV 63 Gas Group 1: Face-down position approximately 10 to 20 minutes after procedure completion 2–49 eyes Off = 50 Group 2: Face-down position immediately after surgery 3–26 eyes Both groups maintained appropriate position for the next 7–10 days 4–4 eyes Dell’Omo [4 ] Prospective observational case series 33 6 cSLO 1–3 On = 11 PPV 15 Gas N/A 2–15 Off = 22 3–9 4–6 Casswell [14 ] Prospective comparative study 70 FC + cSLO Off = 70 PPV 0 Gas Patients randomized to face-down (32/70) or ‘‘bubble-to-break’’ (38/70) for the first 24 h