Comparison of Accelerated and Standard Corneal Collagen Cross-Linking Treatments in Experimental Fungal Keratitis for Aspergillus fumigatus
Table 1
Corneal and corneal epithelium thickness between groups.
Base line mean ± SD 95%CI
28 days after CXL mean ± SD 95%CI
P
Corneal epithelium thickness (μm)
Accelerated CXL (n/n’ = 12/12)
45.36 ± 2.24 43.94 to 46.78
48.13 ± 3.55 45.87 to 50.39
0.0323
Standard CXL (n/n’ = 12/11)
45.48 ± 2.17 44.10 to 46.86
50.67 ± 4.02 47.97 to 53.37
0.0008
P
0.8952
0.1225
Corneal thickness (μm)
Accelerated CXL (n/n’ = 12/12)
383.22 ± 27.35 365.83 to 400.62
537.68 ± 39.32 512.59 to 562.63
<0.0001
Standard CXL (n/n’ = 12/11)
381.80 ± 31.24 362.04 to 401.64
568.24 ± 44.59 538.23 to 598.18
<0.0001
P
0.9068
0.0949
CXL, corneal collagen cross-linking. The test used for statistical analysis among groups was t-test and between groups was one-way ANOVA. n/n’, number of rabbits at base line/number of rabbits with non-healing excluded at 28 days after CXL.