The Efficacy of Anti-VEGF Therapy for Putative or Visible CNV in Central Serous Chorioretinopathy by Optical Coherence Tomography Angiography

Figure 6

Representative image showing the decrease of putative CNV area and resolution of SRF in CSCR patient before and after anti-VEGF treatment. A 50-year-old female patient, who was diagnosed as CSCR with putative CNV in right eye, underwent three consecutive intravitreal injection of anti-VEGF treatments. (a–c) Baseline (before treatment). (a) The putative CNV was visualized as blurred nonhomogeneous hyperreflective signals on the slab of the choriocapillaris on OCTA; (b) The putative CNV in Figure a was outlined using ImageJ to calculate its area; (c) The corresponding OCTA b-scan showed the presence of SRF. (d–f) Treatment (after anti-VEGF treatment). (d) The regression of putative CNV after 3 consecutive anti-VEGF (aflibercept) treatments; (e) The regressed putative CNV area in Figure d was outlined using ImageJ; (f) OCTA b-scan showed complete resolution of SRF after three anti-VEGF treatments.

(a)

(b)

(c)

(d)

(e)

(f)