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Variable | Group | Δ1 Month mean ± SD | Δ3 Months mean ± SD | Δ6 Months mean ± SD | Δ12 Months mean ± SD |
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BCVA | Epi-on | 0.02 ± 0.49 (−0.12–0.45) | −0.01 ± 0.49 (−0.13–0.40) | 0.06 ± 0.51 (−0.11–0.38) | 0.09 ± 0.52 (−0.04–0.37) |
| Epi-off | 0.04 ± 0.44 (−0.04–0.24) | 0.04 ± 0.42 (−0.05–0.31) | 0.05 ± 0.43 (−0.03–0.32) | 0.05 ± 0.42 (−0.04–0.29) |
value | | 0.652 | 0.525 | 0.899 | 0.767 |
Kmax (D) | Epi-on | 1.71 ± 11.89 (−2.74–2.84) | −0.86 ± 12.43 (−2.39–0.02) | 0.65 ± 12.43 (−0.45–0.42) | −0.24 ± 12.49 (−0.29–0.56) |
| Epi-off | 0.98 ± 8.74 (−0.19–2.30) | −0.80 ± 8.69 (−3.19–1.00) | −1.20 ± 8.21 (−2.97–0.62) | −0.91 ± 8.64 (−1.57–1.03) |
value | | 0.576 | 0.818 | 0.213 | 0.406 |
OSDI (score) | Epi-on | −0.48 ± 9.91 (−3.74–5.46) | −1.20 ± 7.68 (−4.93–1.57) | −2.39 ± 7.43 (−6.07–0.85) | −1.06 ± 9.15 (−4.00–3.09) |
| Epi-off | −1.71 ± 10.46 (6.64–0.57) | −1.57 ± 12.01 (−8.05–0.26) | −1.14 ± 9.87 (−1.58–2.27) | −0.90 ± 9.99 (−2.55–1.88) |
value | | 0.112 | 0.107 | 0.254 | 0.896 |
Tear meniscus height (mm) | Epi-on | 0.01 ± 0.08 (−0.01–0.05) | −0.01 ± 0.09 (−0.05–0.02) | −0.02 ± 0.07 (−0.04–0.00) | −0.01 ± 0.08 (−0.05–0.03) |
| Epi-off | 0.00 ± 0.08 (−0.02–0.02) | 0.01 ± 0.08 (−0.02–0.02) | 0.02 ± 0.09 (−0.01–0.04) | 0.01 ± 0.10 (−0.03–0.05) |
value | | 0.226 | 0.208 | 0.036 | 0.615 |
1st NIKBUT (s) | Epi-on | −0.19 ± 5.47 (−3.22–2.54) | 0.62 ± 5.64 (−1.67–2.98) | 1.54 ± 7.21 (−1.87–5.57) | 4.51 ± 7.82 (2.07–9.39) |
| Epi-off | −0.55 ± 7.13 (−4.26–2.81) | 1.02 ± 8.50 (−3.38–5.31) | −0.67 ± 7.45 (−4.95–3.05) | 2.26 ± 9.40 (−1.64–3.85) |
value | | 0.972 | 0.976 | 0.488 | 0.066 |
Average NIKBUT (s) | Epi-on | −0.55 ± 8.53 (−5.17–2.29) | 0.32 ± 7.98 (−2.48–2.68) | 0.10 ± 9.19 (−3.58–4.35) | 1.88 ± 9.55 (0.35–8.27) |
| Epi-off | 0.97 ± 7.93 (−2.32–3.94) | 1.68 ± 8.45 (−2.14–6.38) | 0.72 ± 7.83 (−4.25–4.62) | 4.34 ± 9.30 (−1.51–7.09) |
value | | 0.357 | 0.345 | 1.000 | 0.759 |
Bulbar redness (score) | Epi-on | 0.09 ± 0.61 (−0.09–0.19) | 0.01 ± 0.59 (−0.04–0.20) | −0.05 ± 0.57 (−0.28–0.09) | −0.02 ± 0.53 (−0.24–0.24) |
| Epi-off | −0.09 ± 0.52(−0.21–0.10) | −0.14 ± 0.58 (−0.26–0.05) | −0.12 ± 0.52 (−0.34–0.04) | −0.20 ± 0.46 (−0.63–0.12) |
value | | 0.721 | 0.021 | 0.628 | 0.062 |
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