Review Article

Intravitreal Conbercept with Grid/Focal Photocoagulation for the Treatment of Diabetic Macular Edema: A Systematic Review and Meta-Analysis

Table 1

Study characteristics of included studies.

AuthorsYearStudy designInterventionSamplingAge (year)Jadad scaleFollow-up

Zeng, R.P.2017RCTA12565.1 ± 7.141 mo, 3 mo, 6 mo
B12564.8 ± 6.8

Guo, X.2020RCTIVC (3 injections, no mention of dose) + B3461.8 ± 2.441 wk, 1 mo, 3 mo
B3462.7 ± 2.3

Li, B.J.2017RCTIVC (2 injections of 0.05 mL) + B2059.07 ± 5.12445 d, 3 mo
B2058.47 ± 4.29

Li, B.Y.2020RCTA6045.7 ± 7.3315 d
B6046.1 ± 6.6

Li, Y,Y.2021RCTA5864.39 ± 5.6241 mo, 3 mo, 6 mo
B5863.19 ± 6.12

Li, Y.L.2019RCTIVC (3 injections of 0.05 mL) + B71349.6 ± 12.841 wk, 1 mo, 3 mo, 6 mo
B71348.3 ± 11.7

Nulahou2019RCTA4663.45 ± 6.6343 mo
B4662.10 ± 5.39

Ran, Z.L.2020RCTSingle IVC (no mention of dose) + B4060.95 ± 9.2431 mo, 3 mo, 6 mo
B4060.31 ± 8.37

Tang, J.2017RCTA6051.56 ± 1.4831 mo, 2 mo, 3 mo
B6052.64 ± 1.58

Yang, L.2017RCTsingle IVC (no mention of dose) + B3062.61 ± 6.5943 mo, 6 mo
B3063.14 ± 6.79

Yang, Z.2017RCTIVC (3 injections of 0.05 mL) + B5451.68 ± 10.0241 mo, 2 mo, 3 mo
B5451.60 ± 11.48

Chen, R.2019RCTIVC (3 injections of 0.05 mL) + B6056.72 ± 6.8841 mo, 3 mo
B6056.27 ± 6.82

A: single IVC (0.05~0.1 mL) + B; B: macular focal/grid photocoagulation.