Analysis of Cause-Specific Mortality in Patients with Retinoblastoma
Table 2
Clinical features of 12 RB cause-specific mortality patients.
Patient no. (laterality)
Gender
Age of Dx (months)
IS
Origin
FH
Diagnostic stage (IIRC)
Initial treatment
Treatment after diagnosis
Metastasis
Survival time (months)
Age of death (months)
Last therapy
Direct death reason
Last therapy to death (days)
Last evaluation
Addition
1 (B)
M
25.3
Leukocoria
Referral
No
?/E
En
En, CEV3
No
6.5
31.8
Surgery
Respiratory failure
6
En/S
Should survival
2 (B)
M
2.2
Leukocoria
Primary
No
B/E
IVC
CEV3, laser
No
5.4
7.7
Chemo
Cerebral hemorrhage
13
S/En
Should survival
3 (B)
M
4.4
Leukocoria
Primary
No
D/C
IVC
CEV2
No
1.8
6.2
Chemo
Cerebral hemorrhage
13
T/T
4 (U)
F
15.3
Leukocoria
Primary
No
E+
IVC
CEV4, En, Radio
Yes
7.9
23.2
Radio
Paraplegia
40
En
5 (B)
F
15.1
Low vision
Primary
Father (RB+)
D/D
IAC
IAC2
No
1.4
16.5
Chemo
Intracranial infection
8
T/T
6 (U)
F
97.2
Hypopyon
Referral
No
E
IVC
CTV1
No
8.6
105.8
Chemo
Cerebral hemorrhage
19
S
Should survival
7 (U)
M
4.5
Leukocoria
Primary
No
E
En
En, CTV2
No
1.2
5.7
Chemo
Intracranial infection
7
En
Should survival
8 (U)
F
1.2
Leukocoria
Primary
No
E
IVC
CEV1
No
0.3
1.5
Chemo
Respiratory failure
7
T
9 (U)
M
4.5
Leukocoria
Consulting
No
D
IVC
CEV1
No
0.6
5.1
Chemo
Intracranial infection
12
T
10 (B)
M
22.9
Leukocoria
Primary
No
D/E+
IVC
CEV1, CTV4, intrathecal
Yes (CSF+)
11.5
34.4
Chemo
Intracranial infection
2
T/T
11 (U)
F
1.7
Leukocoria
Primary
No
E
IVC
CTV2, En, CTV1
No
2
3.8
Chemo
Paraplegia
1
En
Should survival
12 (B)
F
17.7
Leukocoria
Primary
No
C/D
IVC
CEV7, IAC11, En CEV6, intrathecal
No
27.1
44.7
Chemo
Intracranial infection
10
T/En
B = bilateral; U = unilateral; S = stable; En = enucleation; T = tumor; M = male; F = female; Dx = diagnosis; IS = initial symptom; FH = family history;? = unclear; CEV = carboplatin, etoposide, vincristine; CTV = carboplatin, teniposide, vincristine; Chemo = chemotherapy; Radio = radiotherapy.
