Research Article

Early OCT Angiography Changes of Macular Neovascularization in Patients with Exudative AMD Treated with Brolucizumab in a Real-World Setting

Table 2

Mean change in central retinal thickness, macular neovascularization size, and best corrected visual acuity of 10 treatment-naïve neovascular age-related macular degeneration patients at baseline and during follow-up.

VisitMean CRT + SD (μm)
-value
Mean MNV size + SD (mm2)
-value
Mean BCVA + SD (logMAR)
-value

Baseline461.7 ± 82.90.85 ± 1.10.67 ± 0.4
4 weeks351.0 ± 39.1
0.75 ± 1.0
0.51 ± 0.4
8 weeks327.9 ± 48.1
0.70 ± 1.0
0.47 ± 0.4
16 weeks333.3 ± 58.4
0.74 ± 1.1
0.478 ± 0.4
20 weeks343.6 ± 74.3
0.75 ± 1.2
0.55 ± 0.4

BCVA = best corrected visual acuity; CRT = central retinal thickness; logMAR = logarithm of minimal angle of resolution; MNV = macular neovascularization; SD = standard deviation two-tailed Student t-test of visit (week) - baseline.