Research Article

Characteristics of Optic Neuritis in South Korean Children and Adolescents: A Retrospective Multicenter Study

Table 1

Clinical demographics of patients with pediatric onset optic neuritis.

Numbers (total)%, or SD (IQR)

Number of patients127100%
Sex (female)7962.2%

Age at onset (years)
 3–62922.8%
 7–93225.2%
 10–122318.1%
 ≥134333.9%
 Mean (median)10.7 (10.3)4.1 (7.3–14.2)

Bilaterality53 (127)41.7%
Pain with eye movement51 (108)47.2%
Disc swelling at presentation83 (124)66.9%
Accompanying headache37 (127)29.1%
White matter lesions on MRI41 (126)32.5%
Preceding febrile illness within 1 month39 (108)36.1%
Vaccination history within 1 month7 (101)6.9%

Visual acuity at presentationTotal = 126
 ≥20/2043.2%
 <20/20-≥ 20/40118.7%
 <20/40-≥ 20/2002822.2%
 <20/200-> counting fingers2620.6%

Counting finger-no light perception5745.2%

Final visual outcome†Total = 100
 Good7676%
 Fair1515%
 Poor99%

SD = standard deviation, IQR = interquartile range. †Visual outcome was categorized as the latest BCVA ≥20/40 with no visual field defect (good), BCVA <20/40∼≥ 20/200 or ≥ 20/40 with permanent visual field defect (fair), and BCVA less than 20/200 (poor).