Research Article

Crosslinking vs. Observation in Fellow Eyes of Keratoconus Patients

Table 1

Patient Characteristics of crosslinked and naïve fellow eyes.

Patient characteristicsOverall
(N = 79)
CXL fellow eye
Group 1
(N = 30)
Naïve fellow eye
Group 2
(N = 49)
value

Mean age at baseline visit (years)24.6 ± 7.922.0 ± 6.826.1 ± 8.20.026
Gender
 Male55 (70%)26 (87%)29 (59%)0.01
 Female24 (30%)4 (13%)20 (41%)
Family history of keratoconus7 (9%)4 (13%)3 (6%)0.21
Ethnicity
 Caucasian45 (57%)20 (67%)25 (51%)0.46
 African American16 (20%)4 (13%)12 (24%)
 South Asian4 (5%)1 (3%)3 (6%)
 East Asian4 (5%)1 (3%)3 (6%)
 Other10 (13%)4 (13%)6 (12%)
Eye characteristics
Eye
 Right39 (49%)16 (53%)23 (47%)0.58
 Left40 (51%)14 (47%)26 (53%)
Atopic disease32 (41%)15 (50%)17 (35%)0.18
Eye rubbing36 (46%)12 (40%)24 (49%)1
Median duration (years) of disease from diagnosis0.3 [.1, 2.0]0.3 [0.1, 2.0]0.8 [0.0, 5.0]0.65
Contact lens
 Scleral7 (9%)1 (3%)6 (12%)0.52
 Rigid gas permeable11 (14%)4 (13%)7 (14%)
 Soft12 (15%)6 (20%)6 (12%)
Apical scar6 (8%)0 (0%)6 (12%)0.081
Vogt striae7 (9%)3 (10%)4 (8%)0.7
Fleischer ring13 (16%)4 (13%)9 (18%)0.76
Cone observed clinically34 (43%)14 (47%)20 (41%)0.63

Values are presented as mean ± SD, median [interquartile range] or as frequency (percentage).