Evaluation of Neurodevelopmental Outcomes in Premature Twins (Multigestations) with Retinopathy of Prematurity Receiving Anti-VEGF: A Comparison Study

Table 3

Comparison of neurodevelopmental outcomes between IVB treated versus non treated preamature multigestation neonates.

	Treated		Diff	95% CI		value
	Yes	No		Lower	Upper
Head up	4.4 ± 1.5	4.4 ± 1.3	0.039	−0.334	0.412	0.838
Laughing	3.8 ± 1.2	3.6 ± 1.3	0.069	−0.135	0.273	0.505
Sit head steady	7.5 ± 1.6	8.1 ± 3	−0.574	−1.368	0.219	0.156
Regard own hand	4 ± 1.3	4 ± 1.3	0.008	−0.197	0.214	0.937
Roll over	5.3 ± 1.3	5.5 ± 2.1	−0.321	−0.832	0.19	0.218
Grasp rattle	5.6 ± 3.2	5.3 ± 1.9	0.193	−0.475	0.861	0.572
Sit no support	11.5 ± 14.8	13.2 ± 19.1	−0.12	−1.128	0.887	0.815
Turn to voice	5.5 ± 5.5	5.3 ± 5.1	−0.013	−0.173	0.146	0.869
Feed self	14.2 ± 8.5	14.3 ± 6	−0.113	−1.418	1.192	0.865
Work for toy	7 ± 2.6	6.8 ± 2.3	0.005	−0.574	0.584	0.987
Stand holding on	13.4 ± 7.4	14.3 ± 15.1	−1.076	−5.3	3.148	0.618
Pass cube	7.6 ± 3	7.1 ± 2.5	0.23	−0.337	0.798	0.426
Sit alone	14.7 ± 3	16.7 ± 15.1	−2.004	−6.134	2.127	0.342
Pull to stand	12 ± 2.7	12.5 ± 5.4	−0.696	−1.8	0.407	0.216
Bangs 2 cubes held in hand	7.6 ± 2.5	7.2 ± 1.8	0.292	−0.246	0.831	0.287
Imitate speech sounds	7.7 ± 3.8	7.2 ± 3.3	−0.02	−0.249	0.209	0.863
Single syllables	11 ± 4.2	11.1 ± 4.3	−0.264	−1.027	0.5	0.498
Wave bye-bye	12.3 ± 3.7	12.2 ± 3.9	−0.192	−0.893	0.51	0.593
Imitate activities	12.6 ± 4.4	12.2 ± 4.5	−0.226	−0.898	0.446	0.51
Walk well	17.5 ± 3.6	18.2 ± 6.9	−0.932	−2.467	0.603	0.234
Stoop and recover	17.2 ± 3.8	17.5 ± 6.4	−0.565	−1.959	0.829	0.427
Scribble	21 ± 8.9	19.7 ± 6.2	0.753	−0.926	2.433	0.379
Put block in cup	14.7 ± 4.6	14.5 ± 4.3	0.011	−0.213	0.234	0.923
Drink from cup	18.1 ± 7.8	17.1 ± 6.1	0.424	−0.751	1.6	0.479
Runs	23.8 ± 4.5	23.6 ± 4.4	0.266	−0.56	1.091	0.528
Walk backwards	24 ± 4.8	24.6 ± 6	0.142	−0.412	0.696	0.615
Remove garment	29.8 ± 9.1	30.6 ± 8.5	−0.215	−1.264	0.833	0.687
Help in house	32.7 ± 9.3	32.6 ± 10.6	−0.155	−1.043	0.734	0.733
Walk up steps	25.3 ± 9.1	24 ± 9.6	0.143	−0.455	0.742	0.639
Kick ball	27.8 ± 8.6	27.2 ± 8.9	0.217	−0.421	0.855	0.505
Put on clothing	35.2 ± 9.1	35.4 ± 9.7	−0.345	−1.38	0.691	0.514
Name pictures	22.4 ± 7.7	23.2 ± 9.7	−0.227	−0.892	0.437	0.502
Jump up	32.3 ± 9.3	32.4 ± 9.9	−0.03	−0.582	0.522	0.916
Balance each foot	36 ± 8.2	35.2 ± 10	−0.035	−0.579	0.508	0.898
Brush teeth with help	37.9 ± 11.1	37.1 ± 11.8	−0.027	−0.079	0.025	0.312
Speech all understandable	27.5 ± 7.7	27.1 ± 7.7	0.608	−0.399	1.614	0.237