Structure-Function Relationship between Cluster Mean Defect and Sector Peripapillary Retinal Nerve Fiber Layer Thickness in Primary Open Angle Glaucoma

Table 1

Demographics of the participants.

	Control group		All POAG individuals		Early group		Moderate group		Advanced group		P
	Mean/median	SD/quartile	Mean/median	SD/quartile	Mean/median	SD/quartile	Mean/median	SD/quartile	Mean/median	SD/quartile
No. of eyes	39		126		43		30		53
Age (years)	40.28	11.12	40.84	10.32	41.58	11.98	39.43	8.26	41.51	10.39	0.538
Gender (female/male)	15/24		39/87		13/30		12/18		14/39		0.256
Global MD (dB)	0.67	0.54	12.25	7.92	4.40	1.06	9.55	1.66	20.58	4.41	≤0.001
Global pRNFLT (μm)	103.51	6.41	60.87	19.30	79.09	14.55	62.30	13.17	45.26	10.17	≤0.001
Cluster MD 1	0	0,0	5.4	0,10	0	0,3.9	4.7	0,5.8	11.6	6.1,21.9	≤0.01
Cluster MD 2	0	0,0	9.9	4.7,23.5	4.0	2.5,6.0	7.8	5.3,11.1	25.4	17.9,29.1	≤0.001
Cluster MD 3	0	0,0	9.9	5,26.1	4.0	0,6.5	8.1	5.9,12.0	27.6	22.1,28.3	≤0.001
Sector pRNFLT 3	143	134,157	80	60,110.5	112	93,138	87	69.8,107.5	58	46.56.7	≤0.001
Sector pRNFLT 4	107	101,121	67	44,94	95	75,106	75	48.5,91	46	31,63.5	≤0.001
Sector pRNFLT 5	71	65,88	56	41,70	71	62,84	57	47,70	39	29,50.5	≤0.001
Sector pRNFLT 6	63	55,71	50.5	40,61.3	59	53,73	49.5	42.8,59.2	40	30.5,49	≤0.001
Sector pRNFLT 7	113	98,133	64.5	46,88	88	67,96	63.5	49,82.3	48	36,62	≤0.001
Sector pRNFLT 8	164	143,179	61.5	45,84	86	57,132	67	48.8,84	47	36.5,64.5	≤0.001
Sector pRNFLT 9	145	129,167	55	39,80	75	54,138	55	43.5,67.8	47	35,57.5	≤0.001
Sector pRNFLT10	76	66,87	51	37,68	67	55,74	53.5	38.5,67.8	40	31,50	≤0.001

MD: mean defect; pRNFLT: peripapillary retinal nerve fiber layer thickness.