The Correlation between Matrix Metalloproteinase-9 Point-of-Care Immunoassay, Tear Film Osmolarity, and Ocular Surface Parameters

Table 4

Comparison of MMP-9 grade and osmolarity between ocular surface parameter groups according to dry eye severity.

	MMP-9 grade		Osmolarity (mOsmol/L)
	Mean ± SD	value	Mean ± SD	value
Corneal staining score
Positive	1.4 ± 1.242	0.768	321.6 ± 19.261	0.018
Negative	1.22 ± 1.093		299.89 ± 16.213
Schirmer’s test I (mm)
<10	1.29 ± 1.213	0.70	311.41 ± 23.071	0.391
≥10	1.43 ± 1.134		318.43 ± 14.07
NIBUT (sec)
<5	1.63 ± 1.506	0.589	315.63 ± 22.155	0.624
≥5	1.19 ± 0.981		312.38 ± 20.746

SD = standard deviation; MMP-9 = matrix metalloproteinase-9; NIBUT = noninvasive tear break up time. Indicates statistical significance ().