The Relationship between Statin and Risk of Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis

Table 4

Subgroup analysis of the relationship between statin consumption and risk of developing age-related macular degeneration.

Characteristics		Study no.	OR (95% CI)	value
Study type	Cross-sectional	2	0.95 (0.59–1.53)	0.831
	Cohort	13	0.95 (0.82–1.09)	0.458
	Case-control	8	0.92 (0.75–1.13)	0.440
Study location	North America and Canada	13	0.94 (0.80–1.10)	0.468
	Europe	4	0.81 (0.54–1.21)	0.308
	Asia	4	1.05 (0.94–1.18)	0.362
	Australia	1	0.52 (0.26–1.04)	0.125
Study period	2000–2010	13	0.91 (0.76–1.08)	0.291
	2011–2021	9	0.95 (0.81–1.11)	0.520
Follow-up period	Less than five years	16	0.90 (0.78–1.04)	0.165
	More than five years	6	0.99 (0.81–1.22)	0.965
Sample size	>10000	10	1.02 (0.90–1.12)	0.983
	≤10000	12	0.79 (0.59–1.06)	0.114