DNA Polymorphism of the LOXL1 Promoter Region in Exfoliation Syndrome in Uygur Individuals in XinJiang, China
Table 6
The haplotype association analysis between these SNPs.
Haplotype
Case (proportion)
Control (proportion)
-value
OR
95% CI
rs12914489
rs4886467
rs4558370
G
G
G
186 (0.431)
307 (0.517)
0.048
0.761
0.581–0.997
A
G
G
22 (0.051)
27 (0.045)
0.988
0.995
0.532–1.862
G
G
T
37 (0.086)
95 (0.160)
＜0.001
0.474
0.308–0.730
G
T
G
187 (0.433)
165 (0.278)
＜0.001
1.909
1.437–2.535
rs4461027
rs4886761
T
C
176 (0.407)
366 (0.616)
＜0.001
0.427
0.324–0.562
C
C
61 (0.141)
75 (0.126)
0.3619
1.200
0.811–1.776
C
T
195 (0.451)
153 (0.258)
＜0.001
2.303
1.729–3.067
The frequencies of haplotypes were significantly different between the two groups except GGG/AGG of SNPs rs12914489, rs4886467, and rs4558370 and CC of SNPs rs4461027 and rs4886761.
