MicroRNA Expression Analysis of Mice Retinas with Oxygen-Induced Retinopathy by RNA Sequencing

Figure 2

(a) Venn diagram of microRNA (miRNA) detected by RNA sequencing. A total of 565 miRNAs were detected in the OIR mouse retina, and 583 miRNAs were detected in the normal group. A total of 553 miRNAs were expressed in both groups. (b) Volcano plots showing dysregulated miRNAs in the OIR group vs. normal group. Compared with the normal group, the expression of 2 miRNAs was significantly upregulated and the expression of 36 miRNAs was significantly downregulated in the OIR group. (c) Heat map of miRNAs expressed at different levels in OIR retinas vs. normal retinas (6 retinas/group). Red indicates a relatively higher expression, and green indicates a lower expression.

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