Regulation of the Inflammatory Response, Proliferation, Migration, and Epithelial-Mesenchymal Transition of Human Lens Epithelial Cells by the lncRNA-MALAT1/miR-26a-5p/TET1 Signaling Axis

Figure 5

Efficiency of MALAT1 interference on proliferation, migration, and EMT of HLECs under inflammatory conditions. (a, b) Evaluation of the effectiveness of TNF-α treatment and MALAT1 siRNAs on the migratory ability of HLECs by wound healing and transwell assays. (c) Evaluation of the effectiveness of TNF-α treatment and siRNAs on the proliferation ability of HLECs by the CCK8 assay. (d, e) Evaluation of the effectiveness of TNF-α treatment and siRNAs on mRNA and protein expressions of EMT marker genes by RT-qPCR and Western blotting. GAPDH served as the endogenous control.

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