Research Article
Lack of Association of Bone Morphogenetic Protein 2 Gene Haplotypes with Bone Mineral Density, Bone Loss, or Risk of Fractures in Men
Table 2
The distribution of BMP2 SNP3 genotype and allele frequencies and odds ratio.
(a) |
| Genotypes | Patients (, %) | Controls (, %) |
| AA | 12 (10.2) | 32 (14.3) | AT | 61 (51.7) | 121 (54.0) | TT | 45 (38.1) | 71 (31.7) | Total | 118 | 224 | HWE value | 0.19 | 0.09 | Alleles | | | *A | 0.36 (±0.029) | 0.41 (±0.022) | *T | 0.64 | 0.59 |
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(b) |
| Allele/genotype | Odd ratios (95% confidence interval), value |
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*A versus *T | 1.25 (0.90–1.73) | AA versus AT | 1.34 (0.65–2.79), | AA versus TT | 1.69 (0.79–3.62), | AA versus AT + TT | 1.47 (0.73–2.98), | Armitage’s trend test | 1.29, |
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