Antimalarial Activity of Nigella sativa L. Seed Extracts and Selection of Resistance in Plasmodium berghei ANKA in a Mouse Model

Table 4

Mean of parasitemia, % parasitemia suppression, and survival time after treatment termination.

Drug/extract	Dose (mg/kg)	Mean ± SD parasitemia (%)	% suppression of parasite	Mean survival time (days)
MeOH	125	7.18 ± 0.73	56.29	10.50 ± 0.58
	250	5.58 ± 0.39	66.05	11.25 ± 0.96
	500	4.03 ± 0.67	75.52	16.25 ± 0.96
EtOAc	125	6.75 ± 0.31	59.02	11.00 ± 0.82
	250	4.72 ± 0.19	71.27	12.40 ± 1.14
	500	4.04 ± 0.87	75.3	15.60 ± 1.52
CQ		1.20 ± 0.23	92.59	28.25 ± 1.50
Vehicle		16.45 ± 3.08		5.00 ± 0.82

The results are expressed as mean ± SD.