Antimalarial Activity of Nigella sativa L. Seed Extracts and Selection of Resistance in Plasmodium berghei ANKA in a Mouse Model

Table 5

Packed cell volume on D0 and D4.

Animal group	Dose	PCV-D0	PCV-D4	% change
Control	0.2 vehicle	53.40 ± 2.30	49.80 ± 2.78	−6.74
	5 mg/kg CQ	52.40 ± 2.07	55.00 ± 1.87	4.96
MeOH	125 mg/kg	53.00 ± 1.00	53.00 ± 1.58	0.00
	250 mg/kg	51.75 ± 1.50	53.25 ± 0.50	2.90
	500 mg/kg	52.40 ± 1.82	53.60 ± 2.88	2.29
Control	0.2 ml vehicle	53.80 ± 2.78	49.80 ± 1.64	−7.43
	5 mg/kg CQ	53.80 ± 2.78	55.80 ± 1.92	3.72
EtOAc	125 mg/kg	53.20 ± 3.03	53.60 ± 1.52	0.75
	250 mg/kg	56.25 ± 3.86	56.75 ± 2.99	0.41
	500 mg/kg	52.40 ± 2.30	53.00 ± 1.58	1.15

The PCV is expressed as mean ± standard deviation.