Research Article

Antimalarial Activity of Nigella sativa L. Seed Extracts and Selection of Resistance in Plasmodium berghei ANKA in a Mouse Model

Table 7

Summary of the ED50, ED90 (mg/ml.day), and resistance index values of ethyl acetate extract measured in the 4-day test during the drug selection pressure assay.

Passage NoEthyl acetate extract
ED50RSIED90RSI

Parent line0.77178.041
5th2.673.4779.101.01
11th4.896.3589.841.15
16th10.0313.03111.631.43