The Pattern of Microorganisms and Drug Susceptibility in Pediatric Oncologic Patients with Febrile Neutropenia

Table 3

Etiology and outcome of 563 febrile neutropenia episodes.

Outcome	Total episodes (n = 563)
Etiology of fever, n (%)
Fever of unknown origin	279 (49.6%)
Microbiologically documented infection	192 (34.1%)
Clinically documented infection	92 (16.3%)
Oropharyngeal infection	26
Skin and soft-tissue infection	17
Upper respiratory tract infection	16
Lower respiratory tract infection	13
Gastrointestinal tract infection	12
Urinary tract infection	6
CNS infection	2
Clinical complication, n (%)
Oxygen therapy	110 (19.5%)
Shock	100 (17.8%)
ICU admission	78 (13.9%)
Mechanical ventilator use	37 (6.6%)
Renal dysfunction	24 (4.3%)
Hepatic dysfunction	8 (1.4%)
Duration of hospitalization in days (median, range)	25 (1, 163)
Mortality within 2 weeks of a febrile episode	21 (3.7%)