Research Article
The Pattern of Microorganisms and Drug Susceptibility in Pediatric Oncologic Patients with Febrile Neutropenia
Table 6
Characteristics of febrile neutropenic children with Gram-negative bacterial infection.
| | Characteristics | Non-antibiotics-resistant bacterial infection (N = 84) (%) | Antibiotics-resistant bacterial infection (N = 20) (%) | value+ |
| | Underlying disease | | | | | Hematologic malignancy | 65 (77.4) | 19 (22.6) | 1 | | Solid tumor | 16 (80) | 4 (20) | 1 | | Therapy preceding infection | | | | | Induction | 19 (22.6) | 11 (55) | 0.006 | | Maintenance | 7 (8.3) | 0 (0) | 0.341 | | Remission stage of underlying | | | | | malignancy | | | | | Complete remission | 18 (21.4) | 8 (40) | 0.093 | | Noncomplete remission | 24 (28.6) | 1 (5) | 0.038 | | Central venous catheter | 45 (53.6) | 13 (65) | 0.454 | | Central line | 26 (31) | 6 (30) | 1 | | PICC line | 16 (19) | 5 (25) | 0.546 | | Chemoport | 2 (2.4) | 0 (0) | 1 | | Hickmann | 1 (1.2) | 0 (0) | 1 | | Site of infection | | | | | Oropharyngeal infection | 1 (1.2) | 0 (0) | 1 | | Skin and soft-tissue infection | 4 (4.8) | 3 (15) | 0.127 | | GI infection | 7 (8.3) | 0 (0) | 0.341 | | Lower respiratory tract infection | 5 (6) | 4 (20) | 0.066 | | Upper respiratory tract infection | 3 (3.6) | 0 (0) | 1 | | Urinary tract infection | 25 (29.8) | 7 (35) | 0.788 |
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value calculated by Fisher’s exact test. |
