Mitochondrial Thioredoxin-Glutathione Reductase from Larval Taenia crassiceps (Cysticerci)

Table 2

Kinetic constants for mTGR using different disulfides as substrates.

Disulfide		mTGR
	${\text{K}}_{\text{m}}$	$k_{\text{cat}}$	$k_{\text{cat}}$ / ${\text{K}}_{\text{m}}$
	($\mu$M)	(S^−1)	(M^−1 S^−1)
Trx-S2T. crassiceps	0.87	0.47	5.4 x 10^5
Trx-S2P. falciparum	28.3	0.81	2.8 x 10^4
Trx-S2H. sapiens	21.3	0.44	2.1 x 10^4
GSSG	41.4	0.84	2.0 x 10^4
DTNB	34.5	0.30	8.7 x 10^3

Date obtained using 100 $\mu$M NADPH at ${25}^{°}$C and pH 7.8.