Mitochondrial Thioredoxin-Glutathione Reductase from Larval Taenia crassiceps (Cysticerci)

Table 3

Comparison of TGRs catalytic efficiencies using thioredoxin or glutathione as substrate.

Enzyme		$k_{\text{cat}}$/${\text{K}}_{\text{m}}$ (${\text{M}}^{-1}{\text{s}}^{-1}$)
	Trx-S2	GSSG	Trx-S2/GSSG
${\text{TGR}}^{\text{a}}$-Mouse testis	$1.89\times {10}^6$	$0.18\times {10}^6\mathrm{\hspace{0.17em}\hspace{0.17em}}$	10.7
${\text{cTGR}}^{\text{b}}$-T. crassiceps	$1.13\times {10}^6$	$0.34\times {10}^6\mathrm{\hspace{0.17em}\hspace{0.17em}}$	3.3
${\text{TGR}}^{\text{c}}$-S. Mansoni	$4.70\times {10}^6$	$3.0\times {10}^5$	15.7
${\text{mTGR}}^{\text{d}}$-T. crassiceps	$5.40\times {10}^5$	$2.2\times {10}^4\mathrm{\hspace{0.17em}\hspace{0.17em}}$	24.5

${}^{\text{a}}$Taken from reference [11] using Trx-E. coli.
${}^{\text{b}}$Taken from reference [15] using Trx P. falciparum.
${}^{\text{C}}$Taken from reference [13] using Trx (natural substrate).
${}^{\text{d}}$This report with Trx (natural substrate).