Research Article

Phytochemical Screening and In Vivo Antimalarial Activity of Two Traditionally Used Medicinal Plants of Afar Region, Ethiopia, against Plasmodium berghei in Swiss Albino Mice

Table 9

Antimalarial activities of crude Chloroform root extracts of S. persica and mean survival time.

Dose mg/kg extract% Parasitaemia ± SEM% SuppressionMST

NC75.92±1.090.006.4±2.44
20058.74±0.7922.62±0.597.4 ±0.63
35055.04±0. 827.89±1.268.2±0.5
50043.6±2.0242.57±4.698.4±0.6
QC0.0010030(+)

Means in a column followed by the same letter do not differ significantly (P>0.05).
Key: values are presented as M±SEM; n=5; CQ= Chloroquine Phosphate; PC=positive control; NC=negative control (0.2ml of 20% DMSO); += maximum days of followup; MST=mean survival time.