First Age- and Gender-Matched Case-Control Study in Australia Examining the Possible Association between Toxoplasma gondii Infection and Type 2 Diabetes Mellitus: The Busselton Health Study
Table 2
Univariate analysis of the variables associated with the seroprevalence of anti-T. gondii IgG antibodies among T2DM patients and control subjects. BHS, Western Australia.
Toxoplasma serology
OR
95% CI
value
T2DM (, %)
Controls (, %)
POS
NEG
POS
NEG
Gender (IgG)
Male
51 (68.0)
24
53 (70.7)
22
0.88
0.44-1.77
0.723
Female
42 (56.0)
33
46 (61.3)
29
0.80
0.42-1.54
0.507
Total
93 (62)
57
99 (66)
51
0.84
0.52-1.35
0.470
Gender (IgM)
Male
5 (6.7)
70
2 (2.7)
73
2.61
0.49-13.88
0.246
Female
3 (4.0)
72
13 (17.3)
62
0.20
0.05-0.73
0.008
Total
8 (5)
142
15 (10)
145
0.51
0.21-1.23
0.129
Health
SOB walking
19
74
11
88
2.05
0.92-4.59
0.076
Chronic cough
15
78
20
79
0.76
0.36-1.59
0.465
Chronic phlegm
16
77
15
84
1.16
0.54-2.51
0.699
Rhinitis
51
42
46
53
1.40
0.79-2.47
0.275
Wheeze
23
70
21
78
1.22
0.62-2.39
0.562
Chest tightness
27
66
19
80
1.72
0.88-3.37
0.110
Disease state
Asthma
20
73
20
79
1.08
0.54-2.17
0.824
Arthritis
42
51
36
63
1.44
0.81-2.57
0.215
Bronchitis
17
76
22
77
0.78
0.39-1.59
0.507
Cancer
4
89
4
95
1.07
0.26-4.40
0.938
Eczema
12
81
10
89
1.32
0.54-3.22
0.542
Food allergies
12
81
8
91
1.69
0.66-4.33
0.274
Hay fever
28
65
26
73
1.21
0.64-2.27
0.554
Other chest
12
81
10
89
1.32
0.54-3.22
0.542
Pleurisy
8
85
7
92
1.24
0.43-3.56
0.693
Pneumonia
17
76
18
81
1.01
0.48-2.10
0.996
Sinusitis
21
72
19
80
1.23
0.61-2.47
0.563
Pet ownership
Cat ownership
13
80
22
77
0.57
0.27-1.21
0.140
Dog ownership
41
52
37
62
1.32
0.74-2.35
0.344
Other pet ownership
16
77
19
80
0.87
0.42-1.82
0.721
Body mass index (BMI, kg/m2)
Underweight: <18.5
0
0
1
0
—
—
—
Normal: 18.5-24.9
11
10
30
20
0.73
0.26-2.05
0.553
Overweight: 25.0-29.9
40
22
44
16
0.66
0.66-1.43
0.293
Obese: >30.0
42
24
24
15
1.09
0.48-2.48
0.830
Waist
,
53
32
33
16
0.8
0.38-1.68
0.561
: number of subjects; POS: number of subjects in which anti-IgG antibodies were detected; NEG: number of subjects in which anti-IgG antibodies were not detected; OR: odds ratio; 95% CI: 95% confidence interval; SOB: shortness of breath; M: male; F: female.
