Protective Effects of Gymnema inodorum Leaf Extract on Plasmodium berghei-Induced Hypoglycemia, Dyslipidemia, Liver Damage, and Acute Kidney Injury in Experimental Mice

Figure 4

Effect of GIE on AST, ALT, and ALP during PbANKA infection. Groups of ICR mice were inoculated with parasitized erythrocytes of PbANKA by intraperitoneal injection. GIE at the doses of 100, 250, and 500 mg/kg were administered orally once a day for 4 consecutive days. CQ (10 mg/kg) was given as positive control. Blood was collected for measurement of (a) AST, (b) ALT, and (c) ALP. , , and , compared to H. ^## and ^###, compared to UN. H: healthy mice; UN: untreated mice; GI100, GI250, and GI500: treated mice with 100, 250, and 500 mg/kg of GIE; CQ: 10 mg/kg of chloroquine-treated mice. Results were expressed as the .

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