Research Article
Angiotensin Receptor Blocker and Neprilysin Inhibitor Suppresses Cardiac Dysfunction by Accelerating Myocardial Angiogenesis in Apolipoprotein E-Knockout Mice Fed a High-Fat Diet
Table 2
Cardiac functions by echocardiography in pre and posttreatment.
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
CTL: control group; VAL: valsartan group; SAC: sacubitril group; VAL/SAC: valsartan plus sacubitril group; HR: heart rate; IVSTd: interventricular septum thickness diameter; LVPWd: left ventricular posterior wall thickness diameter; LVDd: left ventricular internal dimension in diastole; LVDs: left ventricular internal dimension in systole; LVEF: left ventricular ejection fraction; LVFS: left ventricular fractional shortening. , †, and ‡ show significant differences compared to CTL, VAL, and SAC, respectively. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||