The Association of Serum AIM2 Level with the Prediction and Short-Term Prognosis of Coronary Artery Disease

Table 1

Baseline characteristics of the study population.

Variables	Control group ()	CAD group ()	value
Age (years)			0.053
Male (, %)	54 (56.3)	118 (64.5)	0.179
BMI (kg/m^2)			0.218
SBP (mmHg)			0.054
DBP (mmHg)			0.507
HR (bpm)	78 (70, 88)	78 (70, 86)	0.368
Smoke (, %)	27 (28.1)	66 (36.1)	0.181
Past histories
Hypertension (, %)	61 (63.5)	135 (73.8)	0.076
DM (, %)	20 (20.8)	57 (31.1)	0.067
Hyperlipidemia (, %)	9 (9.4)	32 (17.5)	0.069
Af (, %)	4 (4.2)	15 (8.2)	0.204
Stroke (, %)	15 (15.6)	41 (22.4)	0.179
Echocardiography
LA (cm)	3.8 (3.5, 4.1)	3.9 (3.6, 4.2)	0.050
LV (cm)	4.6 (4.4, 4.9)	4.7 (4.3, 5.1)	0.440
LVEF (%)	67 (63, 71)	66 (60, 70)	0.076
Laboratory parameters
WBC (×10^9/L)	5.7 (4.8, 6.6)	6.8 (5.6, 8.2)	<0.001
RBC (×10^12/L)	4.7 (4.2, 5.0)	4.6 (4.2, 4.9)	0.700
Hb (g/L)	137 (127, 144)	138 (126, 149)	0.510
Plt (×10^9/L)			0.141
Hct (%)			0.481
TSB (μmol/L)	12.7 (10.5, 16.2)	11.9 (9.5, 15.9)	0.092
ALT (μmol/L)	25 (17, 32)	23 (18, 34)	0.917
AST (μmol/L)	25 (19, 33)	23 (19, 32)	0.585
BUN (mmol/L)	5.9 (4.8, 7.2)	5.9 (4.8, 7.1)	0.933
Scr (μmol/L)	67 (58, 78)	68 (57, 82)	0.490
UA (μmol/L)	319 (287, 377)	331 (266, 406)	0.741
Cystatin C (mg/L)	0.8 (0.7, 1.0)	0.9 (0.8, 1.1)	<0.001
TG (mmol/L)	1.5 (1.0, 2.1)	1.2 (0.9, 1.8)	0.091
TC (mmol/L)	3.6 (3.0, 4.2)	3.7 (3.0, 4.5)	0.261
HDL-C (mmol/L)	1.2 (1.0, 1.3)	1.1 (1.0, 1.3)	0.328
LDL-C (mmol/L)	2.0 (1.6, 2.4)	2.1 (1.6, 2.6)	0.388
Apoa (mg/L)	139 (75, 252)	120 (58, 254)	0.394
eGFR-MDRD ()	101.3 (85.5, 110.7)	101.3 (84.0, 118.9)	0.814
Medications
Aspirin (, %)	0 (0.0)	165 (90.2)	<0.001
ADP-receptor blocker (, %)	0 (0.0)	136 (74.3)	<0.001
Statin (, %)	6 (6.3)	178 (97.3)	<0.001
Beta-blocker (, %)	20 (20.8)	134 (73.2)	<0.001
ACEI/ARB (, %)	36 (37.5)	86 (47.0)	0.129
CCB (, %)	31 (32.3)	57 (31.1)	0.845
Diuretic (, %)	13 (13.5)	49 (26.8)	0.012

Data are presented as (%), mean and standard deviation, or median (25th, 75th). CAD: coronary artery disease; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; HR: heart rate; DM: diabetes mellitus; Af: atrial fibrillation; LA: left atrium; LV: left ventricle; LVEF: left ventricular ejection fraction; WBC: white blood cell; RBC: red blood cell; Hb: hemoglobin; Plt: platelet; Hct: hematocrit; TSB: total serum bilirubin; ALT: alanine aminotransferase; AST: aspartate aminotransferase; BUN: blood urea nitrogen; Scr: serum creatinine; UA: uric acid; TG: triglyceride; TC: total cholesterol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; Apoa: apolipoprotein (a); eGFR-MDRD: estimated glomerular filtration rate based on MDRD equation; ADP: adenosine diphosphate; ACEI: angiotensin-converting enzyme inhibitor; ARB: angiotensin receptor blocker; CCB: calcium channel blocker.