Review Article
Associations between AGT M235T Polymorphism and Cancer: An Updated Meta-Analysis
Table 3
Summary ORs and 95% CI of AGT M235T polymorphism with cancer risk.
| | Variables | a | T vs. M | TT vs. MM | TM vs. MM | Dominant model | Recessive model | | OR (95% CI) | Model | OR (95% CI) | Model | OR (95% CI) | Model | OR (95% CI) | Model | OR (95% CI) | Model |
| | Total | 9 | 0.96 (0.72-1.29) | R | 1.28 (0.80-2.04) | R | 0.90 (0.53-1.52) | R | 0.93 (0.55-1.57) | R | 1.13 (0.83-1.52) | R | | Race | | | | | | | | | | | | | Asian | 2 | 0.82 (0.57-1.19) | R | 0.89 (0.40-2.01) | F | 1.06 (0.47-2.39) | F | 0.94 (0.42-2.08) | F | 0.78 (0.46-1.31) | R | | Caucasian | 6 | 1.00 (0.67-1.51) | R | 1.50 (0.81-2.80) | R | 0.97 (0.52-1.83) | R | 1.01 (0.53-1.93) | R | 1.27 (0.83-1.97) | R | | Cancer type | | | | | | | | | | | | | Breast cancer | 2 | 1.13 (0.85-1.50) | F | 1.13 (0.48-2.63) | R | 0.66 (0.23-1.84) | R | 0.81 (0.35-1.89) | R | 1.53 (0.97-2.43) | F | | Digestive cancer | 4 | 1.12 (0.87-1.44) | R | 1.26 (0.73-2.16) | R | 1.19 (0.98-1.44) | F | 1.15 (0.96-1.38) | F | 1.10 (0.76-1.59) | R | | Quality | | | | | | | | | | | | | High | 7 | 1.05 (0.87-1.27) | R | 1.19 (0.82-1.74) | R | 1.13 (0.95-1.35) | F | 1.11 (0.94-1.32) | F | 1.08 (0.80-1.45) | R | | Low | 2 | 0.62 (0.07-5.48) | R | 0.49 (0.01-41.59) R | | 0.57 (0.03-12.34) | R | 0.58 (0.02-14.93) | R | 0.66 (0.05-8.64) | R |
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aNumber of comparisons; OR: odds ratio; CI: confidence interval; R: random model; F: fixed model.
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