The Effect of the Angiotensin-Converting Enzyme Inhibitor on Bone Health in Castrated Hypertensive Rats Is Mediated via the Kinin-Kallikrein System

Figure 5

Effect of captopril and HOE140 on bone turnover markers in castrated hypertensive rats. (a) Captopril increased rat urine DPD/Cr concentration. Compared to captopril, HOE140 decreased urine DPD/Cr in male rats. (b) Captopril increased rat serum OC concentration. Compared to captopril, HOE140 decreased osteocalcin concentration in male rats. Data are shown as . , . , , , , , and .

(a)

(b)