Fibrinogen-to-Albumin Ratio Predicts Postcontrast Acute Kidney Injury in Patients with Non-ST Elevation Acute Coronary Syndrome after Implantation of Drug-Eluting Stents

Table 2

Baseline characteristics among three groups.

Variable	T 1	T 2	T 3	value
	290	291	291
Male (, %)	207 (71.4)	170 (58.4)	177 (60.8)	0.003
Age (years)				0.001
BMI (kg/m^2)				0.698
Prior stroke (, %)	64 (22.1)	56 (19.2)	66 (22.7)	0.558
Hypertension (, %)	203 (70.0)	209 (71.8)	215 (73.9)	0.581
Diabetes (, %)	75 (25.9)	96 (33.0)	94 (32.3)	0.120
Smoking (, %)	86 (29.7)	84 (28.9)	74 (25.4)	0.483
Anemia (, %)	27 (9.3)	39 (13.4)	62 (21.3)	<0.001
CKD (, %)	9 (3.1)	4 (1.4)	7 (2.4)	0.375
NSTEMI (, %)	47 (16.2)	35 (12.0)	73 (25.1)	<0.001
CHF (, %)	15 (5.2)	26 (8.9)	43 (14.8)	<0.001
SBP (mmHg)				0.713
DBP (mmHg)				0.366
Leukocyte (10^9/L)	6.2 (5.2, 7.3)	6.5 (5.6, 7.9)	6.8 (5.8, 8.1)	<0.001
Hemoglobin (g/L)				<0.001
Platelet (10^9/L)	198 (164, 232)	196 (163, 237)	199 (170, 243)	0.224
Fasting blood glucose (mmol/L)	5.8 (5.2, 6.9)	5.8 (5.2, 7.2)	5.9 (5.2, 7.9)	0.564
SCr (μmol/L)	74 (63, 86)	74 (64, 86)	78 (67, 91)	0.006
eGFR (mL/min/1.73 m^2)	91.0 (77.8, 102.3)	86.2 (72.3, 98.3)	81.3 (68.5, 95.9)	<0.001
Uric acid (μmol/L)	350 (295, 406)	335 (288, 412)	364 (297, 417)	0.101
Triglyceride (mmol/L)	1.5 (1.0, 2.2)	1.4 (1.0, 2.0)	1.5 (1.1, 2.1)	0.471
TC (mmol/L)	4.5 (3.7, 5.1)	4.4 (3.7, 5.2)	4.5 (3.8, 5.2)	0.585
HDL-C (mmol/L)	1.1 (1.0, 1.3)	1.1 (0.9, 1.3)	1.1 (0.9, 1.2)	0.020
LDL-C (mmol/L)	2.7 (2.1, 3.3)	2.6 (2.0, 3.3)	2.7 (2.1, 3.4)	0.422
PT ()				0.825
APTT ()				0.622
D-dimer (μg/L)	71 (43, 119)	95 (55, 153)	113 (66, 181)	<0.001
Fibrinogen (g/L)				<0.001
Albumin (g/L)				<0.001
FAR (%)				<0.001
Mehran score	1 (1, 4)	4 (1, 5)	4 (1, 6)	<0.001
HbA1c (%)	6.0 (5.5,6.5)	6.1 (5.7, 6.9)	6.1 (5.6, 7.1)	0.008
LVEF (%)	68 (63, 72)	67 (63, 72)	67 (60, 73)	0.617
Procedural characteristics
Left main disease (, %)	16 (5.5)	19 (6.5)	26 (8.9)	0.252
Three-vessel disease (, %)	99 (34.1)	108 (37.1)	130 (44.7)	0.027
Number of stents				0.992
Contrast volume (mL)	100 (100, 100)	100 (100, 100)	100 (100, 100)	0.938
Hydration (, %)	255 (87.9)	237 (81.4)	222 (76.3)	0.001
Medication use (, %)
Aspirin	285 (98.3)	284 (97.6)	288 (99.0)	0.433
Clopidogrel/ticagrelor	289 (99.7)	291 (100)	290 (99.7)	0.443
ACEI/ARB	155 (53.4)	157 (54.0)	173 (59.5)	0.271
β-Blockers	215 (74.1)	227 (78.0)	241 (82.8)	0.039
Statin	288 (99.3)	290 (99.7)	291 (100)	0.248
Diuretics	20 (6.9)	31 (10.7)	45 (15.5)	0.004
PC-AKI (, %)	18 (6.2)	25 (8.6)	71 (24.4)	<0.001

PC-AKI: postcontrast acute kidney injury; BMI: body mass index; CKD: chronic kidney disease; NSTEMI: non-ST elevation myocardial infarction; CHF: congestive heart failure; SBP: systolic blood pressure; DBP: diastolic blood pressure; SCr: serum creatinine; eGFR: estimated glomerular filtration rate; TC: total cholesterol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; PT: prothrombin time; APTT: activated partial thromboplastin time; FAR: fibrinogen-to-albumin ratio; HbA1c: hemoglobin A1c; LVEF: left ventricular ejection fraction; ACEI: angiotensin-converting enzyme inhibitor; ARB: angiotensin receptor blocker.