Polymorphisms in the Renin-Angiotensin System and eNOS Glu298Asp Genes Are Associated with Increased Risk for Essential Hypertension in a Mexican Population
Table 3
MTHFR C677T genotype and allele frequency in patients with essential hypertension and controls.
Patients ()
Controls ()
value
OR (95% CI)
Genotype
C/C,
51 (22.8)
60 (28.8)
0.12
(0.86–1.93)
C/T,
105 (46.8)
95 (45.7)
T/T,
68 (30.4)
53 (25.5)
Dominant model
T/T vs. C/T+C/T,
68 vs.
53 vs.
0.26
(0.82–1.99)
Recessive model
C/C vs. C/T+T/T,
51 vs.
60 vs.
0.15
(0.87–2.17)
Allele frequency
C,
207 (46.2)
215 (51.7)
0.11
(0.94–1.64)
T,
241 (53.8)
201 (48.3)
Data presented are number and % of patients. CI: confidence interval; odds ratio, .
