Polymorphisms in the Renin-Angiotensin System and eNOS Glu298Asp Genes Are Associated with Increased Risk for Essential Hypertension in a Mexican Population

Table 4

ACE I/D genotype and allele frequency in patients with essential hypertension and controls.

	Patients; ()	Controls; ()	value	OR (95% CI)
Genotype
I/I,	68 (30.4)	83 (39.9)	0.02	1.36 (1.04–2.01)
I/D,	112 (50.0)	98 (47.1)
D/D,	44 (19.6)	27 (13.0)
Dominant model
D/D vs. I/D+D/D,	44 vs.	27 vs.	0.02	1.92 (1.08–3.44)
Recessive model
I/I vs. I/D+D/D,	68 vs.	83 vs.	0.04	1.52 (1.00–2.31)
Allele frequency
I,	248 (57.9)	264 (63.2)	0.02	1.40 (1.06–1.86)
D,	200 (42.1)	152 (36.8)

Data presented are number and % of patients. CI: confidence interval; odds ratio, .