Polymorphisms in the Renin-Angiotensin System and eNOS Glu298Asp Genes Are Associated with Increased Risk for Essential Hypertension in a Mexican Population

Table 5

AGT M235T genotype and allele frequency in patients with essential hypertension and controls.

	Patients; ()	Controls; ()	value	OR (95% CI)
Genotype
M/M,	128 (37.1)	140 (67.3)	0.004	1.32 (1.11–2.04)
M/T,	72 (32.1)	60 (28.9)
T/T,	24 (10.8)	8 (3.8)
Dominant model
T/T vs. M/T+T/T,	24 vs.	8 vs.	0.006	3.0 (1.25–7.45)
Recessive model
M/M vs. M/T+T/T,	128 vs.	140 vs.	0.03	1.54 (1.02–2.33)
Allele frequency
M,	328 (73.2)	340 (81.75)	0.003	1.64 (1.17–2.30)
T,	120 (26.8)	76 (18.25)

Data presented are number and % of patients. CI: confidence interval; odds ratio, .