Polymorphisms in the Renin-Angiotensin System and eNOS Glu298Asp Genes Are Associated with Increased Risk for Essential Hypertension in a Mexican Population
Table 7
AGTR1 A1166C genotype and allele frequency in patients with essential hypertension and controls.
Patients ()
Controls ()
value
OR (95% CI)
Genotype
A/A,
148 (66.1)
135 (64.9)
0.85
0.98 (0.78–1.49)
A/C,
58 (25.9)
61 (29.3)
C/C,
18 (8.0)
12 (5.8)
Dominant model
A/A vs. A/C+C/C,
148 vs.
135 vs.
0.87
0.97 (0.64–1.47)
Recessive model
C/C vs. A/C+A/A,
18 vs.
12 vs.
0.35
1.43 (0.63–3.24)
Allele frequency
A,
354 (79.0)
331 (79.6)
0.84
1.03 (0.73–1.46)
C,
94 (21.0)
85 (20.4)
Data presented are number and % of patients. CI: confidence interval; odds ratio, .